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This document was written not to replace existing biosafety guidelines, but to 1) improve the safety of activities in clinical diagnostic laboratories, 2) encourage laboratory workers to think about safety issues they might not previously have considered or addressed, and 3) encourage laboratorians to create and foster a culture of safety in their laboratories.Should any of the guidelines provided herein conflict with federal, state, or local laws or regulatory requirements, the laboratorian should defer to the federal, state, or local requirements.Throughout these guidelines, quality laboratory science is reinforced by a common-sense approach to biosafety in day-to-day activities.Because many of the same diagnostic techniques are used in human and animal diagnostic laboratories, the text is presented with this in mind.Warde Medical Laboratory, Ann Arbor, MI The material in this report originated in the National Center for Emerging and Zoonotic Infectious Diseases, Beth P. Telephone: 678-428-6319; Fax: 770-396-0955; E-mail: [email protected] Summary Prevention of injuries and occupational infections in U. BMBL-5, however, was not designed to address the day-to-day operations of diagnostic laboratories in human and animal medicine. Michael Miller, Ph D, Microbiology Technical Services, LLC, Dunwoody, GA 30338. CDC and the National Institutes of Health addressed the topic in their publication Biosafety in Microbiological and Biomedical Laboratories, now in its 5th edition (BMBL-5).
A specific section for veterinary diagnostic laboratories addresses the veterinary issues not shared by other human laboratory departments.
Recommendations for all laboratories include use of Class IIA2 biological safety cabinets that are inspected annually; frequent hand washing; use of appropriate disinfectants, including dilutions of household bleach; dependence on risk assessments for many activities; development of written safety protocols that address the risks of chemicals in the laboratory; the need for negative airflow into the laboratory; areas of the laboratory in which use of gloves is optional or is recommended; and the national need for a central site for surveillance and nonpunitive reporting of laboratory incidents/exposures, injuries, and infections.
This report offers guidance and recommends biosafety practices specifically for human and animal clinical diagnostic laboratories and is intended to supplement the 5th edition of Biosafety in Microbiological and Biomedical Laboratories (BMBL-5), developed by CDC and the National Institutes of Health (1).
This culture of safety is also supported by the Clinical and Laboratory Standards Institute (2). Bureau of Labor Statistics, in 2008, approximately 328,000 medical laboratory technicians and technologists worked in human diagnostic laboratories in the United States.
These guidelines promote a culture of safety and include recommendations that supplement BMBL-5 by addressing the unique needs of the diagnostic laboratory.
They are not requirements but recommendations that represent current science and sound judgment that can foster a safe working environment for all laboratorians.